Evidence for a mouse pathogenicity locus in certain temperature-sensitive mutants of foot-and-mouth disease virus.
- Published Article
Infection and immunity
- Publication Date
Jun 01, 1977
Serial tissue culture passaging of three foot-and-mouth disease temperature-sensitive mutants demonstrated the stability of their temperature sensitivity and mouse avirulence characteristics. Recovery of mouse-virulent temperature-sensitive viruses after passage of the mutants in mice suggested that these were not covariant expressions of the same locus, but were under the control of different genes.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/197007