Affordable Access

Evidence for 12-lipoxygenase induction in the vessel wall following balloon injury.

Authors
  • Natarajan, R
  • Pei, H
  • Gu, J L
  • Sarma, J M
  • Nadler, J
Type
Published Article
Journal
Cardiovascular research
Publication Date
Feb 01, 1999
Volume
41
Issue
2
Pages
489–499
Identifiers
PMID: 10341849
Source
Medline
License
Unknown

Abstract

These results indicate for the first time that balloon injury results in marked induction of 12-LO mRNA and protein expression in the vessel wall. Furthermore, LO pathway activation may mediate, at least in part, the development of the lesion or plaque instability, suggesting a novel target for therapeutic intervention to block these pathological events.

Report this publication

Statistics

Seen <100 times