Affordable Access

Evaluation of the in vitro susceptibility and emergence of mutants resistant to ciprofloxacin among multidrug resistant clinical isolates.

Authors
  • Lopes, C. A.
  • Mendes, R. P.
  • Curi, P. C.
  • Watanabe, D. S.
  • Decarlis, R. M.
  • Horácio, A.
  • Michelin, L. A.
  • Placidelli, B. A.
Publication Date
Oct 01, 1993
Source
Acervo Digital da Unesp
Keywords
Language
English
License
White
External links

Abstract

Two hundred and seventy-seven multidrug resistant clinical isolates [K. pneumoniae, (N = 87); E coli, (N = 30); Salmonella typhimurium (N = 100); P. aeruginosa, (N = 30); S. aureus, (N = 30)] from hospitalized patients specimens, were tested in vitro for sensitivity to Ciprofloxacin. Application of the disk diffusion test and determination of the minimal inhibitory concentration by the microdilution method indicated that, almost all isolates were sensitive to the drug. Overall, S. aureus and P. aeruginosa were the less sensitive organisms. Ciprofloxacin-resistant mutants occurred at frequencies of > or = 10(-5)/CFU.

Report this publication

Statistics

Seen <100 times