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Evaluation of serum and tissue levels of alpha-tocopherol.

Authors
  • Brandt, R B
  • Kaugars, G E
  • Riley, W T
  • Bei, R A
  • Silverman, S Jr
  • Lovas, J G
  • Dezzutti, B P
  • Chan, W
Type
Published Article
Journal
Biochemical and molecular medicine
Publication Date
Feb 01, 1996
Volume
57
Issue
1
Pages
64–66
Identifiers
PMID: 8812727
Source
Medline
License
Unknown

Abstract

This study was designed to test the effect of supplementation of several antioxidants, including alpha-tocopherol, on the clinical reduction of premalignant oral lesions. Samples of oral mucosa and serum were taken from baseline to 9 months of supplementation from patients with premalignant oral lesions and analyzed for alpha-tocopherol by HPLC. Statistical increases in both serum and tissue alpha-tocopherol were found after supplementation. There was no statistical relationship between alpha-tocopherol and beta-carotene levels.

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