Affordable Access

Evaluation of seaFAST, a rapid fluorescent in situ hybridization test, for detection of Helicobacter pylori and resistance to clarithromycin in paraffin-embedded biopsy sections.

Authors
  • Morris, Julie M
  • Reasonover, Alisa L
  • Bruce, Michael G
  • Bruden, Dana L
  • McMahon, Brian J
  • Sacco, Frank D
  • Berg, Douglas E
  • Parkinson, Alan J
Type
Published Article
Journal
Journal of clinical microbiology
Publication Date
Jul 01, 2005
Volume
43
Issue
7
Pages
3494–3496
Identifiers
PMID: 16000488
Source
Medline
License
Unknown

Abstract

A commercially available rapid fluorescent in situ hybridization (FISH) test, (seaFAST H. pylori Combi-Kit; SeaPro Theranostics International, Lelystad, The Netherlands) was used to simultaneously detect the presence of Helicobacter pylori and determine clarithromycin susceptibility in paraffin-embedded biopsy sections. The FISH method was found to be 97% sensitive, 94% specific for the detection of H. pylori and comparable to agar dilution for the detection of resistance to clarithromycin.

Report this publication

Statistics

Seen <100 times