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Evaluation of a rapid method of determination of plasma fibrinogen in swine.

Authors
Type
Published Article
Journal
Canadian journal of comparative medicine : Revue canadienne de médecine comparée
Publication Date
Volume
41
Issue
2
Pages
202–205
Identifiers
PMID: 861838
Source
Medline
License
Unknown

Abstract

An evaluation was made of a rapid semiautomated method for determining fibrinogen level in swine plasma. This method, referred to as thrombin time method or fibrometer method, is based on the principle that when thrombin is added to suitably diluted plasma, the time of clotting is linearly related to the fibrinogen concentration. The linear regression model for the standard curve prepared using swine plasma had an r value of 0.998. A comparison between the fibrometer and the Grannis methods done on 189 swine plasma samples showed good correlation between these two mehtods (r value 0.847). It was concluded that although the fibrometer method may not be as precise as the Grannis method, it would still be acceptable for clinical use in swine.

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