Affordable Access

Evaluation of Techniques for Detection of Carbapenem-Resistant Klebsiella pneumoniae in Stool Surveillance Cultures

Authors
  • D. Landman
  • J. K. Salvani
  • S. Bratu
  • J. Quale
Publisher
American Society for Microbiology
Publication Date
Nov 01, 2005
Source
PMC
Keywords
License
Unknown

Abstract

Screening for gastrointestinal colonization with multidrug-resistant nosocomial pathogens is an important component of infection control protocols. In the New York City region, carbapenem-resistant Klebsiella pneumoniae strains, which harbor the KPC carbapenem-hydrolyzing β-lactamase, have rapidly emerged. The potential utility of screening medium, which involved using 10-μg imipenem disks, was investigated. The method of placing a sample from a fecal surveillance culture into broth containing an imipenem disk appeared to have the greatest sensitivity for detecting KPC-producing K. pneumoniae. Gastrointestinal colonization with two other carbapenem-resistant nosocomial pathogens, Pseudomonas aeruginosa and Acinetobacter baumannii, was also detected using this method. Placing fecal surveillance specimens into broth containing an imipenem disk is an easy method for screening samples for carbapenem-resistant nosocomial pathogens.

Report this publication

Statistics

Seen <100 times