Affordable Access

Evaluation of a new optical immunoassay for diagnosis of neonatal chlamydial conjunctivitis.

Authors
  • Roblin, P M
  • Gelling, M
  • Kutlin, A
  • Tsumura, N
  • Hammerschlag, M R
Type
Published Article
Journal
Journal of clinical microbiology
Publication Date
Feb 01, 1997
Volume
35
Issue
2
Pages
515–516
Identifiers
PMID: 9003631
Source
Medline
License
Unknown

Abstract

The BioStar OIA Chlamydia test (BioStar, Inc., Boulder, Colo.) is a novel immunoassay system that uses changes in reflection of light to directly detect chlamydial antigen in clinical specimens. We compared the optical immunoassay (OIA) with culture for detecting Chlamydia trachomatis in ocular specimens from infants with suspected chlamydial conjunctivitis. We initially performed a retrospective evaluation, testing 152 ocular specimens previously collected for culture with the OIA. The sensitivity and specificity were 94.2 and 97%, respectively. A subsequent prospective study evaluating 37 ocular specimens from infants with suspected C. trachomatis conjunctivitis revealed a sensitivity and specificity of 100 and 92.6%, respectively.

Report this publication

Statistics

Seen <100 times