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Evaluation of intracameral injection of ranibizumab and bevacizumab on the corneal endothelium by scanning electron microscopy.

Authors
  • Ari, Seyhmus
  • Nergiz, Yusuf
  • Aksit, Ihsan
  • Sahin, Alparslan
  • Cingu, Kursat
  • Caca, Ihsan
Type
Published Article
Journal
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Publication Date
Mar 01, 2015
Volume
31
Issue
2
Pages
100–105
Identifiers
DOI: 10.1089/jop.2014.0005
PMID: 25574702
Source
Medline
License
Unknown

Abstract

The SEM examination pointed out deterioration in endothelial cell morphology after intracameral injection of 1 and 0.5 mg ranizumab. However, the effects of intracameral bevacizumab injection on corneal endothelial cells were similar to those found in fellow eyes and the control group. Further large-scale studies that examine the cellular changes by transmission electron microscopy are required to support the results of the present study that evaluates the structural changes in endothelial cells by SEM.

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