A simple method for the determination of three parameters of human interferon status: serum interferon (IFN) and induction of alpha- and gamma-IFN in specimens of 10-fold-diluted whole blood in a volume of 200 microliters is described. Standard parameters of interferon status of normal subjects in the whole blood are given which can be visually presented as a triangle of interferon status, and its deviations in various pathological conditions. The whole-blood method is recommended for large-scale clinical surveys, especially in pediatrics.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/2461615