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[Evaluation of the interferon status of human subjects by whole-blood specimens].

Authors
Type
Published Article
Journal
Voprosy virusologii
Publication Date
Volume
33
Issue
4
Pages
433–436
Identifiers
PMID: 2461615
Source
Medline
License
Unknown

Abstract

A simple method for the determination of three parameters of human interferon status: serum interferon (IFN) and induction of alpha- and gamma-IFN in specimens of 10-fold-diluted whole blood in a volume of 200 microliters is described. Standard parameters of interferon status of normal subjects in the whole blood are given which can be visually presented as a triangle of interferon status, and its deviations in various pathological conditions. The whole-blood method is recommended for large-scale clinical surveys, especially in pediatrics.

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