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Evaluation of blood vessels and edema in the airways of asthma patients: regulation with clarithromycin treatment.

Authors
  • Chu, H W
  • Kraft, M
  • Rex, M D
  • Martin, R J
Type
Published Article
Journal
Chest
Publication Date
Aug 01, 2001
Volume
120
Issue
2
Pages
416–422
Identifiers
PMID: 11502638
Source
Medline
License
Unknown

Abstract

Our data suggest that angiogenesis and edema may not be significant features of airway remodeling in patients with chronic, mild-to-moderate asthma. Clarithromycin treatment in asthmatic patients could reduce the edematous area as identified by alpha(2)-macroglobulin staining, which may lead to airway tissue shrinkage and cause an artificial increase in the number of blood vessels.

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