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Eukaryotic Ribosome as a Target for Cardiovascular Disease

Authors
  • Pellegrino, Simone
  • Yusupova, Gulnara
Publication Date
Nov 17, 2016
Source
HAL-UPMC
Keywords
Language
English
License
Unknown
External links

Abstract

Cardiovascular diseases have been associated with genetic variants and increased plasma level of the secreted protein PCSK9. In this issue of Cell Chemical Biology, Petersen et al. (2016) describe an inhibitor of PCSK9 secretion in human cells that, surprisingly, targets the 80S ribosome.

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