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Ethanol is self-administered into the nucleus accumbens shell, but not the core: evidence of genetic sensitivity.

Authors
  • Engleman, Eric A
  • Ding, Zheng-Ming
  • Oster, Scott M
  • Toalston, Jamie E
  • Bell, Richard L
  • Murphy, James M
  • McBride, William J
  • Rodd, Zachary A
Type
Published Article
Journal
Alcoholism Clinical and Experimental Research
Publisher
Wiley (Blackwell Publishing)
Publication Date
Dec 01, 2009
Volume
33
Issue
12
Pages
2162–2171
Identifiers
DOI: 10.1111/j.1530-0277.2009.01055.x
PMID: 19764930
Source
Medline
License
Unknown

Abstract

The present results indicate that the AcbSh, but not AcbC, is a neuroanatomical structure that mediates the reinforcing actions of EtOH. The data also suggest that, compared to Wistar rats, the AcbSh of P rats is more sensitive to the reinforcing effects of EtOH.

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