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Ethanol-enhanced cytotoxicity of alkylating agents.

Authors
Type
Published Article
Journal
Alcoholism, clinical and experimental research
Publication Date
Volume
26
Issue
3
Pages
381–385
Identifiers
PMID: 11923592
Source
Medline
License
Unknown

Abstract

The results are consistent with impairment of DNA repair processes, particularly base excision repair, by acetaldehyde, as a mechanism by which ethanol increases the genotoxicity of certain genotoxic agents.

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