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Etanercept and anakinra can prolong febrile episodes in patients with hyperimmunoglobulin D and periodic fever syndrome.

Authors
  • Shendi, Hiba M
  • Walsh, Deirdre
  • Edgar, J David M
Type
Published Article
Journal
Rheumatology international
Publication Date
Jan 01, 2012
Volume
32
Issue
1
Pages
249–251
Identifiers
DOI: 10.1007/s00296-009-1322-8
PMID: 20020131
Source
Medline
License
Unknown

Abstract

Hyperimmunoglobulin D and periodic fever syndrome (HIDS) is a rare, hereditary autoinflammatory condition, characterized by recurrent inflammatory episodes. There is no proven treatment for HIDS, but various drugs including, non-steroidal anti-inflammatory drugs, colchicine, steroids, statins and thalidomide have all been tried. Recently, some patients have demonstrated a good clinical response to either etanercept or anakinra. We report a case of a 10-year-old girl who experienced prolonged and severe inflammatory attacks, when she was treated with etanercept, and later with anakinra.

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