The administration of rhEPO brought about increased survival and attenuation of the hepatic injury. This was associated with decreased hepatic NF-κB and JNK activation and thus TNF-α and IL-1β levels. These findings have important implications for the potential use of rhEPO in FHF.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/21516061