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[Errors in the diagnosis and therapy of chronic lympholeukemias].

Authors
  • Iakhnina, E I
  • Astsaturov, I A
  • Pivnik, A V
  • Samoĭlova, R S
  • Kremenetskaia, A M
  • Vorob'ev, A I
Type
Published Article
Journal
Terapevticheskiĭ arkhiv
Publication Date
Jan 01, 1995
Volume
67
Issue
7
Pages
45–49
Identifiers
PMID: 7482305
Source
Medline
License
Unknown

Abstract

The analysis of 67 cases of benign, progressive, tumor CLL, lymph node lymphocytoma, CLL sarcoma transformation showed that the cases were misdiagnosed in 35.8% cases. The most common mistake (25.4%) was aggressive chemotherapy based on histological diagnosis of prolymphocytic, prolymphocytic-lymphoblastic lymphosarcoma without consideration of cytological and clinical evidence, tumor phenotype. The authors think valid to use the following criteria in diagnosis of lymphoproliferative diseases: histological findings, clinical manifestations and blood picture, tumor cell cytology, primary location and predominant dissemination of the tumor, immunophenotype, characteristic chromosomal disorders, response to treatment.

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