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ErbB2 growth factor receptor, a marker for neuroendocrine cells?

Authors
  • Standop, Jens
  • Andrianifahanana, Mahefatiana
  • Moniaux, Nicolas
  • Schneider, Matthias
  • Ulrich, Alexis
  • Brand, Randall E
  • Wisecarver, James L
  • Bridge, Julia A
  • Büchler, Markus W
  • Adrian, Thomas E
  • Batra, Surinder K
  • Pour, Parviz M
Type
Published Article
Journal
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Publication Date
Jan 01, 2005
Volume
5
Issue
1
Pages
44–58
Identifiers
PMID: 15775699
Source
Medline
License
Unknown

Abstract

ErbB2 appears to play an important role in neuroendocrine tissues and is probably involved in the development and functional regulation of these cells. The concomitant expression of these factors and islet cell hormones very likely results in the activation of multiple growth-promoting pathways in pancreatic cancer and its aggressive behavior.

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