Epidermolysis bullosa: preliminary observations of blister formation in keratinocyte cultures.
- Published Article
The British journal of dermatology
- Publication Date
Nov 01, 1984
Keratinocytes from patients with different types of epidermolysis bullosa (EB) demonstrated an abnormal tendency to blister or bleb formation after 14-22 days in culture. The changes were most marked in samples from cases of junctional EB and were not observed in control cultures of normal skin. These findings suggest the possibility of a primary abnormality of keratinocyte adhesion in different varieties of EB and that keratinocyte culture should provide a useful model for further studies on disorders of adhesion in EB.
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This record was last updated on 07/01/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/6208928