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Epidemiology and burden of systemic lupus erythematosus in a Southern European population: data from the community-based lupus registry of Crete, Greece.

Authors
  • Gergianaki, Irini1, 2
  • Fanouriakis, Antonis3
  • Repa, Argyro1
  • Tzanakakis, Michalis1
  • Adamichou, Christina1
  • Pompieri, Alexandra1
  • Spirou, Giorgis1
  • Bertsias, Antonios4
  • Kabouraki, Eleni1
  • Tzanakis, Ioannis5
  • Chatzi, Leda4, 6, 7
  • Sidiropoulos, Prodromos1, 2
  • Boumpas, Dimitrios T2, 3, 8, 9, 10
  • Bertsias, George K1, 2
  • 1 Department of Rheumatology, Clinical Immunology and Allergy, University of Crete School of Medicine, Heraklion, Greece. , (Greece)
  • 2 Laboratory of Autoimmunity and Inflammation, Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece. , (Greece)
  • 3 4th Department of Medicine, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece. , (Greece)
  • 4 Department of Social Medicine, University of Crete School of Medicine, Heraklion, Greece. , (Greece)
  • 5 Department of Nephrology, General Hospital of Chania, Chania, Greece. , (Greece)
  • 6 Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
  • 7 Department of Genetics and Cell Biology, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands. , (Netherlands)
  • 8 Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Athens, Greece. , (Greece)
  • 9 Medical School, University of Cyprus, Nicosia, Cyprus. , (Cyprus)
  • 10 Biomedical Research Foundation of the Academy of Athens, Athens, Greece. , (Greece)
Type
Published Article
Journal
Annals of the Rheumatic Diseases
Publisher
BMJ
Publication Date
Dec 01, 2017
Volume
76
Issue
12
Pages
1992–2000
Identifiers
DOI: 10.1136/annrheumdis-2017-211206
PMID: 28780511
Source
Medline
Keywords
License
Unknown

Abstract

By the use of a comprehensive methodology, we describe the full spectrum of SLE from the community to tertiary care, with almost half of the cases having mild disease, yet with significant damage accrual. SLE is not rare, affects predominantly middle-aged women and is increasingly recognised in men. Neuropsychiatric disease is an emerging frontier in lupus prevention and care.

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