Affordable Access

Access to the full text

Epidemiology of Anthropometric Factors in Glioblastoma Multiforme—Literature Review

Authors
  • Simińska, Donata1
  • Korbecki, Jan1
  • Kojder, Klaudyna
  • Kapczuk, Patrycja1
  • Fabiańska, Marta
  • Gutowska, Izabela
  • Machoy-Mokrzyńska, Anna
  • Chlubek, Dariusz1
  • Baranowska-Bosiacka, Irena1
  • 1 (D.C.)
Type
Published Article
Journal
Brain Sciences
Publisher
MDPI AG
Publication Date
Jan 16, 2021
Volume
11
Issue
1
Identifiers
DOI: 10.3390/brainsci11010116
PMID: 33467126
PMCID: PMC7829953
Source
PubMed Central
Keywords
Disciplines
  • Review
License
Green

Abstract

Although glioblastoma multiforme (GBM) is a widely researched cancer of the central nervous system, we still do not know its full pathophysiological mechanism and we still lack effective treatment methods as the current combination of surgery, radiotherapy, and chemotherapy does not bring about satisfactory results. The median survival time for GBM patients is only about 15 months. In this paper, we present the epidemiology of central nervous system (CNS) tumors and review the epidemiological data on GBM regarding gender, age, weight, height, and tumor location. The data indicate the possible influence of some anthropometric factors on the occurrence of GBM, especially in those who are male, elderly, overweight, and/or are taller. However, this review of single and small-size epidemiological studies should not be treated as definitive due to differences in the survey methods used. Detailed epidemiological registers could help identify the main at-risk groups which could then be used as homogenous study groups in research worldwide. Such research, with less distortion from various factors, could help identify the pathomechanisms that lead to the development of GBM.

Report this publication

Statistics

Seen <100 times