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Eosinophilic fasciitis. Case report and review of the literature.

Authors
  • Bennett, R M
  • Herron, A
  • Keogh, L
Type
Published Article
Journal
Annals of the rheumatic diseases
Publication Date
Aug 01, 1977
Volume
36
Issue
4
Pages
354–359
Identifiers
PMID: 901033
Source
Medline
License
Unknown

Abstract

Eosinophilic fasciitis is a recently described rheumatic disease, some 20 cases having been reported in abstract form. Previous descriptions have stressed the localized nature of skin involvement, the absence of visceral changes or Raynaud's phenomenon, an association with hypergammaglobulinaemia and eosinophilia, and a good response to corticosteroid therapy. The most conspicuous feature of this entity has been a massive thickening of the subcutaneous fascia, when an adequate (skin down to muscle) biopsy has been performed. We report another case conforming to these general features, with the exception that Raynaud's phenomenon was a prominent symptom. A critical review of the literature suggests that eosinophilic fasciitis should tentatively be regarded as a variant of scleroderma.

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