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[Enzymatic protective systems of saliva in inflammation of the periodontium].

Authors
  • Vavilova, T P
  • Petrovich, Iu A
  • Malyshkina, L T
Type
Published Article
Journal
Patologicheskaia fiziologiia i èksperimental'naia terapiia
Publication Date
Jan 01, 1991
Issue
1
Pages
32–34
Identifiers
PMID: 2057229
Source
Medline
License
Unknown

Abstract

The activity of some glycosidases, trypsin-like proteinases, peroxidase, inhibitors of beta-glucuronidase and trypsin-like proteinases, as well as the amount of thiocyanates were studied in mixed saliva (MS), dental deposit (DD) and gums (G) of patients with inflammation of the periodontium. In periodontitis the activity of beta-glucuronidase increases fourfold and that of beta-galactosidase doubles in the G; the activity of beta-glucuronidase and its inhibitors increases, the activity of proteinases diminishes, and the antitryptic activity increases in MS, the activity of peroxidase and the amount of thiocyanates change in this case. Along with the peroxidase-H2O2-thiocyanates system, the inhibitors of beta-glucuronidase and trypsin-like proteinases possess properties of unspecific protection, preventing destruction of the periodontal tissues by glycosides and proteinases of microbial and animal origin.

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