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Enterococci highly resistant to penicillin: characterizing isolates from Singapore hospitals.

Authors
Type
Published Article
Journal
Singapore Medical Journal
0037-5675
Publisher
Singapore Medical Journal
Publication Date
Volume
32
Issue
4
Pages
252–253
Identifiers
PMID: 1776005
Source
Medline
License
Unknown

Abstract

Enterococci are increasing in importance as nosocomial pathogens and causes of severe sepsis in immunocompromised patients. From September to November 1989, a survey of 898 enterococcal isolates showed that 52 had acquired high-level resistance to penicillin and ampicillin (MIC greater than 100 mg/l). These were all Enterococcus faecium, did not produce beta-lactamase and showed high-level resistance to gentamicin and streptomycin as well. The majority were urinary isolates, but a few caused bacteraemia in severely ill patients. The potential spread of these highly-resistant enterococci would limit the therapeutic options for systemic infections.

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