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Enteral feeding induces early intestinal adaptation in a parenterally fed neonatal piglet model of short bowel syndrome.

Authors
  • Dodge, M Elaine
  • Bertolo, Robert F
  • Brunton, Janet A
Type
Published Article
Journal
JPEN. Journal of parenteral and enteral nutrition
Publication Date
Mar 01, 2012
Volume
36
Issue
2
Pages
205–212
Identifiers
DOI: 10.1177/0148607111417447
PMID: 22190604
Source
Medline
License
Unknown

Abstract

This new model demonstrated profound SI adaptation, initiated early postsurgery by polyamine synthesis and crypt cell proliferation and only in response to enteral feeding. These changes translated to greater gut mass and length within days, likely improving functional capacity long term.

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