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Enteral feeding of a chemically defined diet preserves pulmonary immunity but not intestinal immunity: the role of lymphotoxin beta receptor.

Authors
Type
Published Article
Journal
JPEN. Journal of parenteral and enteral nutrition
Publication Date
Volume
31
Issue
6
Pages
477–481
Identifiers
PMID: 17947602
Source
Medline
License
Unknown

Abstract

Route and type of nutrition differentially influence molecular events in the intestinal and respiratory mucosal immune systems. Enteral feeding with any diet (complex or chemically defined) maintains lung LTbetaR expression, whereas intestinal LTbetaR levels are maintained only with CEDs (chow and CED). We hypothesize that LTbetaR is responsible for the observed preservation of respiratory tract immunity with administration of a noncomplex, chemically defined enteral diet, whereas intestinal immunity is compromised with this diet.

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