Enlargement of the membranous ventricular septum: an internal stigma of Down's syndrome.
- Published Article
The Journal of Pediatrics
- Publication Date
Oct 01, 1974
A study of heart specimens without ventricular septal defect from patients with down's syndrome showed a significant enlargement of the membranous ventricular septum as compared to the normal heart. This increase in area of the ventricular septum occupied by membranous tissue from 2 to 9% may not only predispose patients with Down's syndrome to congenital heart disease, but may be one end of a spectrum of cardiac anomalies related to malalignment or maldevelopment of the ventricular septum in Down's syndrome.
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This record was last updated on 07/01/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/4280438