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Endothelin receptor-A is required for the recruitment of antitumor T cells and modulates chemotherapy induction of cancer stem cells.

Authors
  • Coffman, Lan
  • Mooney, Collin
  • Lim, Jaeyoung
  • Bai, Shoumei
  • Silva, Ines
  • Gong, Yusong
  • Yang, Kun
  • Buckanovich, Ronald J
Type
Published Article
Journal
Cancer Biology & Therapy
Publisher
Landes Bioscience
Publication Date
Feb 01, 2013
Volume
14
Issue
2
Pages
184–192
Identifiers
DOI: 10.4161/cbt.22959
PMID: 23192269
Source
Medline
Keywords
License
Unknown

Abstract

These studies indicate a critical role for ETRA in the regulation of immune cell recruitment and in the CSC resistance to chemotherapy.

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