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Endothelial Dysfunction in Vascular Encephalopathy

Authors
  • Verjugina, N. I.1
  • Chimagomedova, A. Sh.1
  • Starovoitova, I. M.1
  • Levin, O. S.1
  • 1 Russian Medical Academy of Continuing Professional Education, Moscow, Russia , Moscow (Russia)
Type
Published Article
Journal
Neuroscience and Behavioral Physiology
Publisher
Springer US
Publication Date
Apr 26, 2019
Volume
49
Issue
4
Pages
444–450
Identifiers
DOI: 10.1007/s11055-019-00753-9
Source
Springer Nature
Keywords
License
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Abstract

This review addresses endothelial dysfunction as a component in the pathogenesis of vascular encephalopathy (VE), which is particularly severe in lesions of the small cerebral vessels. The authors consider the possible mechanisms of impairment of endothelial function in VE and the characteristics of the neuroanatomy and pathophysiology of the endothelium of the cerebral vessels. Laboratory and instrumented methods for the diagnosis of endothelial dysfunction are discussed, along with approaches to its correction.

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