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Endothelial cell activation in patients with decompensated heart failure.

Authors
  • Colombo, Paolo C
  • Banchs, Javier E
  • Celaj, Sulejman
  • Talreja, Ashok
  • Lachmann, Justine
  • Malla, Shailesh
  • DuBois, Nicholas B
  • Ashton, Anthony W
  • Latif, Farhana
  • Jorde, Ulrich P
  • Ware, J Anthony
  • LeJemtel, Thierry H
Type
Published Article
Journal
Circulation
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Jan 04, 2005
Volume
111
Issue
1
Pages
58–62
Identifiers
PMID: 15611373
Source
Medline
License
Unknown

Abstract

Clinical decompensation in CHF is associated with activation of the venous endothelium. Return to a compensated state after short-term inotropic therapy results in a significant reduction in endothelial nitrotyrosine formation, COX-2, and iNOS expression.

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