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Endoscopic Diagnosis and Management of Barrett’s Esophagus with Low-Grade Dysplasia

Authors
  • maione;, francesco
Publication Date
May 23, 2022
Identifiers
DOI: 10.3390/diagnostics12051295
OAI: oai:mdpi.com:/2075-4418/12/5/1295/
Source
MDPI
Keywords
Language
English
License
Green
External links

Abstract

Barrett’s Esophagus is a common condition associated with chronic gastroesophageal reflux disease. It is well known that it has an association with a higher incidence of esophageal adenocarcinoma, but this neoplastic transformation is first preceded by the onset of low and high-grade dysplasia. The evaluation of low grade dysplastic esophageal mucosa is still controversial; although endoscopic surveillance is preferred, several minimally invasive endoscopic therapeutic approaches are available. Endoscopic mucosal resection and radiofrequency ablation are the most used endoscopic treatments for the eradication of low-grade dysplasia, respectively, for nodular and flat dysplasia. Novel endoscopic treatments are cryotherapy ablation and argon plasma coagulation, that have good rates of eradication with less complications and post-procedural pain.

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