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Endogenous DNA Damage and Repair Enzymes: -A short summary of the scientific achievements of Tomas Lindahl, Nobel Laureate in Chemistry 2015.

Authors
  • Klungland, Arne1
  • Yang, Yun-Gui2
  • 1 Department of Microbiology, Division of Diagnostics and Intervention, Institute of Clinical Medicine, Oslo University Hospital, Rikshospitalet, Oslo NO-0027, Norway; Department of Molecular Medicine, Faculty of Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo NO-0027, Norway. Electronic address: [email protected]
  • 2 CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: [email protected]
Type
Published Article
Journal
Genomics, proteomics & bioinformatics
Publication Date
June 2016
Volume
14
Issue
3
Pages
122–125
Identifiers
DOI: 10.1016/j.gpb.2015.11.001
PMID: 26689322
Source
Medline
License
Unknown

Abstract

Tomas Lindahl completed his medical studies at Karolinska Institute in 1970. Yet, his work has always been dedicated to unraveling fundamental mechanisms of DNA decay and DNA repair. His research is characterized with groundbreaking discoveries on the instability of our genome, the identification of novel DNA repair activities, the characterization of DNA repair pathways, and the association to diseases, throughout his 40 years of scientific career.

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