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Endocrine profiles in six patients with acanthosis nigricans.

Authors
Type
Published Article
Journal
The Journal of the Association of Physicians of India
Publication Date
Volume
42
Issue
7
Pages
529–530
Identifiers
PMID: 7868520
Source
Medline
License
Unknown

Abstract

Six women (age range 17-38 years), who presented to the dermatology services with biopsy-proven acanthosis nigricans of variable duration were evaluated to rule out endocrine diseases. Menstrual abnormalities (5/6 patients), pallid striae (4/6 patients), hirsutism (4/6 patients) and acne vulgaris (2/6 patients) were found on physical examination. All the patients had body mass indices in the obese (> 27 kg/m2) range, and in association we found ovarian hyperthecosis, PCOD, premature ovarian failure, glucose intolerance and hyperprolactinaemia in the above six patients. The importance of appropriate endocrinal evaluation in patients with biopsy-proven acanthosis nigricans is emphasized.

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