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Emissive terbium probe for multiphoton in vitro cell imaging.

Authors
  • Law, Ga-Lai
  • Wong, Ka-Leung
  • Man, Cornelia Wing-Yin
  • Wong, Wing-Tak
  • Tsao, Sai-Wah
  • Lam, Michael Hon-Wah
  • Lam, Paul Kwan-Sing
Type
Published Article
Journal
Journal of the American Chemical Society
Publisher
American Chemical Society
Publication Date
Mar 26, 2008
Volume
130
Issue
12
Pages
3714–3715
Identifiers
DOI: 10.1021/ja710418d
PMID: 18321106
Source
Medline
License
Unknown

Abstract

A polymeric terbium complex that can be excited by near-infrared excitation at 800 nm via multiphoton absorption processes has been synthesized. This complex has been demonstrated to show strong, observable, three-photon-induced f-f emission in cell imaging. In vitro studies carried out in three carcinoma cell lines (A549, HONE1, and HeLa) have been performed and shown to have low cytotoxicity. This complex is therefore a potential candidate for future infrared excitation imaging dyes.

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