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An emerging allergen: Cannabis sativa allergy in a climate of recent legalization

Authors
  • Jackson, Bradley1
  • Cleto, Erica2
  • Jeimy, Samira2, 3
  • 1 London Health Sciences Centre, London, ON, Canada , London (Canada)
  • 2 Western University, London, ON, Canada , London (Canada)
  • 3 B3-112, St. Joseph’s Healthcare London, 268 Grosvenor Street, London, ON, N6A 4V2, Canada , London (Canada)
Type
Published Article
Journal
Allergy, Asthma & Clinical Immunology
Publisher
BioMed Central
Publication Date
Jun 26, 2020
Volume
16
Issue
1
Identifiers
DOI: 10.1186/s13223-020-00447-9
Source
Springer Nature
Keywords
License
Green

Abstract

Considering its recent legalization in Canada, the health implications of Cannabis sativa exposure, including allergy, are coming to the forefront of medical study and interest. C. sativa allergy is an issue that affects recreational users of the substance, processors, agricultural workers, and contacts of Cannabis aeroallergens and secondhand product. Allergies to C. sativa are heterogenous and span the spectrum of hypersensitivity, from dermatitis to rhinoconjunctivitis to life-threatening anaphylaxis. Due to its recent legalization, sensitized individuals will have increasing exposure from direct contact to agricultural pollens. Diagnosis and treatment of Cannabis allergy are developing fields that are already showing promise in the identification of culprit antigens and the potential for immunotherapy; however, much responsibility still falls on clinical diagnosis and symptom management. Hopefully, given the current explosion of interest in and use of Cannabis, C. sativa allergy will continue to garner awareness and therapeutic strategies.

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