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[Elimination of admixtures from antibiotic sediments during their treatment with solvents].

Authors
  • Sinitsyn, M A
  • Zhukovskaia, S A
  • Murav'eva, S A
Type
Published Article
Journal
Antibiotiki
Publication Date
Dec 01, 1984
Volume
29
Issue
12
Pages
897–901
Identifiers
PMID: 6524891
Source
Medline
License
Unknown

Abstract

A model for determination of the admixture concentration in the secondary mother solution was developed. The concentration was determined depending on the solvent volume used for repulping the precipitate and on the impurity level of the initial antibiotic paste. When the values of X1 and X2 are known it is possible to estimate the amount of the admixtures remaining in the paste layer after separation of the secondary mother solution with regard to the volume of the latter in the precipitate pores. Optimization of paste repulping should be considered in combination with displacement washing and the apparatus used for separation of the phases, as well as the requirements for the purity level of the finished product.

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