Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles
- Authors
- Type
- Published Article
- Journal
- Nature Communications
- Publisher
- Springer Nature
- Publication Date
- Dec 02, 2019
- Volume
- 10
- Issue
- 1
- Identifiers
- DOI: 10.1038/s41467-019-13316-w
- Source
- Springer Nature
- License
- Green
Abstract
Oncogenic exosomes can circulate in the blood, but their selective removal has not been possible. Here the authors show that aptamer-functionalised mesoporous silica nanoparticles can find to a specific population of circulating exosomes and eliminate them via the hepatobiliary route.