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Elevation of serum immunoglobulin free light chains during the preclinical period of rheumatoid arthritis.

Authors
  • Deng, Xiaoli
  • Crowson, Cynthia S
  • Rajkumar, S Vincent
  • Dispenzieri, Angela
  • Larson, Dirk R
  • Therneau, Terry M
  • Matteson, Eric L
  • Kyle, Robert A
  • Katzmann, Jerry A
  • Gabriel, Sherine E
  • Davis, John M 3rd
Type
Published Article
Journal
The Journal of rheumatology
Publication Date
Feb 01, 2015
Volume
42
Issue
2
Pages
181–187
Identifiers
DOI: 10.3899/jrheum.140543
PMID: 25593227
Source
Medline
Keywords
License
Unknown

Abstract

Elevation of serum FLC precedes the development of RA and may be useful in monitoring B cell activity and disease progression. FLC are associated with mortality among patients with RA as well as the general population.

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