Affordable Access

Elevated pleural fluid levels of defensins in patients with empyema.

Authors
  • Ashitani, J
  • Mukae, H
  • Nakazato, M
  • Taniguchi, H
  • Ogawa, K
  • Kohno, S
  • Matsukura, S
Type
Published Article
Journal
Chest
Publication Date
Mar 01, 1998
Volume
113
Issue
3
Pages
788–794
Identifiers
PMID: 9515858
Source
Medline
License
Unknown

Abstract

Our results suggest that the high effusion concentrations of defensins in pleural effusion may constitute an important component of the host defense system or may have a cytotoxic role in empyema. Our results also indicate that the high levels of IL-8 and G-CSF in empyema may indirectly explain the elevated levels of defensins by increasing the number of neutrophils in the pleural space.

Report this publication

Statistics

Seen <100 times