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Elevated Expression of Zinc Finger Protein 703 Promotes Cell Proliferation and Metastasis through PI3K/AKT/GSK-3β Signalling in Oral Squamous Cell Carcinoma.

Authors
  • Wang, Hao1
  • Deng, Xubin2
  • Zhang, Jinshan1
  • Ou, Zhilin1
  • Mai, Jiajie1
  • Ding, Shangwei3
  • Huo, Shaofen4
  • 1 Department of Radiation Oncology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. , (China)
  • 2 Department of Medical Oncology, Affiliated Cancer Hospital of Guangzhou Medical University, Guangzhou, China. , (China)
  • 3 Department of Ultrasound, Dongguan People's Hospital Affiliated to Southern Medical University, Dongguan, China. , (China)
  • 4 Department of otorhinolaryngology of Nanfang Hospital, Southern Medical University, Guangzhou, China. , (China)
Type
Published Article
Journal
Cellular Physiology and Biochemistry
Publisher
S. Karger AG
Publication Date
Jan 01, 2017
Volume
44
Issue
3
Pages
920–934
Identifiers
DOI: 10.1159/000485360
PMID: 29176314
Source
Medline
Keywords
License
Unknown

Abstract

The results show that ZNF703 promotes cell growth and metastasis through PI3K/Akt/GSK-3β signalling in OSCC and that it may be a promising target in the treatment of patients with OSCC.

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