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Electron microscopic findings of transverse fission of M. leprae by freeze-etching methods.

Authors
Type
Published Article
Journal
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
Publication Date
Volume
53
Issue
2
Pages
247–250
Identifiers
PMID: 3894540
Source
Medline

Abstract

The structures of multiplication by transverse fission found in the lepromas and livers of nude mice and nine-banded armadillos inoculated with Mycobacterium leprae isolated from human lepromas, a nine-banded armadillo with naturally acquired leprosy-like disease, and a nine-banded armadillo inoculated with M. leprae isolated from the mangabey monkey with naturally acquired leprosy infection are described. The images of multiplication by transverse fission of M. leprae were almost always found inside the phagolysosomes of lepra cells. At the time of multiplication by transverse fission, band structures were observed generally at both sides of the fission line. According to these results, multiplication of M. leprae by transverse fission is done inside the phagolysosomes of lepra cells of nude mice and nine-banded armadillos.

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