Electrolyte metabolism in patients with periodic affective disorders during treatment with rubidium.
- Published Article
- Publication Date
Jan 01, 1983
Five patients suffering from periodic affective disorders with short mood-cycles were treated with rubidium chloride, producing peak erythrocyte concentrations between 9 and 13 mmol/l. Loading with rubidium was associated with decreased total body potassium, but red-cell potassium was unchanged. Regular mood-cycling was disturbed, together with the associated body-weight changes. There was a slight extracellular "metabolic" acidosis. Electrolyte concentrations fluctuate abnormally in these patients, and two muscle biopsy specimens had very low potassium contents.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/6419259