Affordable Access

deepdyve-link
Publisher Website

Electrochemical intramolecular C-H amination: synthesis of benzoxazoles and benzothiazoles.

Authors
  • Morofuji, Tatsuya
  • Shimizu, Akihiro
  • Yoshida, Jun-Ichi
Type
Published Article
Journal
Chemistry - A European Journal
Publisher
Wiley (John Wiley & Sons)
Publication Date
Feb 16, 2015
Volume
21
Issue
8
Pages
3211–3214
Identifiers
DOI: 10.1002/chem.201406398
PMID: 25641711
Source
Medline
Keywords
License
Unknown

Abstract

A new method for metal-free intramolecular C-H amination has been developed. Electrochemical oxidation of 2-pyrimidyloxybenzenes and 2-pyrimidylthiobenzenes, which can be easily prepared from phenols and thiophenols, respectively, followed by the treatment of the resulting pyrimidinium ions with piperidine gives 2-aminobenzoxazoles and 2-aminobenzothiazoles, respectively.

Report this publication

Statistics

Seen <100 times