Affordable Access

deepdyve-link
Publisher Website

Electrocardiographic characteristics and SCN5A mutations in idiopathic ventricular fibrillation associated with early repolarization.

Authors
  • Watanabe, Hiroshi
  • Nogami, Akihiko
  • Ohkubo, Kimie
  • Kawata, Hiro
  • Hayashi, Yuka
  • Ishikawa, Taisuke
  • Makiyama, Takeru
  • Nagao, Satomi
  • Yagihara, Nobue
  • Takehara, Naofumi
  • Kawamura, Yuichiro
  • Sato, Akinori
  • Okamura, Kazuki
  • Hosaka, Yukio
  • Sato, Masahito
  • Fukae, Satoki
  • Chinushi, Masaomi
  • Oda, Hirotaka
  • Okabe, Masaaki
  • Kimura, Akinori
  • And 7 more
Type
Published Article
Journal
Circulation Arrhythmia and Electrophysiology
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Dec 01, 2011
Volume
4
Issue
6
Pages
874–881
Identifiers
DOI: 10.1161/CIRCEP.111.963983
PMID: 22028457
Source
Medline
License
Unknown

Abstract

We found reductions in heart rate and cardiac conduction and loss-of-function mutations in SCN5A in patients with idiopathic ventricular fibrillation associated with early repolarization. These findings support the hypothesis that decreased sodium current enhances ventricular fibrillation susceptibility.

Report this publication

Statistics

Seen <100 times