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Electrical stimulation of the kindled hippocampus briefly increases extracellular dopamine in the nucleus accumbens.

Authors
  • Strecker, R E1
  • Moneta, M E
  • 1 Department of Psychiatry and Behavioral Science, State University of New York at Stony Brook, NY 11794-8790.
Type
Published Article
Journal
Neuroscience Letters
Publisher
Elsevier
Publication Date
Aug 01, 1994
Volume
176
Issue
2
Pages
173–177
Identifiers
PMID: 7830940
Source
Medline
License
Unknown

Abstract

The effect of electrical stimulation of the dorsal hippocampus on accumbens dopamine release was examined. Stimulation of the kindled hippocampus that produced stage 3 seizures evoked a brief increase in extracellular DA and DOPAC levels in the contralateral nucleus accumbens. In contrast, similar stimulation early in the development of kindling producing a stage 1 seizure did not evoke this increase.

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