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Efficacy study of intensive cis-platin therapy in advanced non-small cell bronchogenic carcinoma.

Authors
  • Vogl, S E
  • Berenzweig, M
  • Camacho, F
  • Greenwald, E
  • Kaplan, B H
Type
Published Article
Journal
Cancer
Publication Date
Jul 01, 1982
Volume
50
Issue
1
Pages
24–26
Identifiers
PMID: 7044518
Source
Medline
License
Unknown

Abstract

Thirty patients with advanced non-small cell bronchogenic carcinoma were treated with cis-platin, 75 mg/M2 weekly for three weeks, then every three weeks. Eighteen were ambulatory, 22 had distant metastases, 14 had prior irradiation, and none had prior chemotherapy. Ten patients (33%) had objective remissions lasting a median of three months. Responders lived a median of five months, compared to three months for nonresponders. Transient mild azotemia was noted in twelve patients. Cis-platin has definite but modest activity in non-small cell bronchogenic carcinoma.

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