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Efficacy and safety of fluticasone furoate/vilanterol compared with fluticasone propionate/salmeterol combination in adult and adolescent patients with persistent asthma: a randomized trial.

Authors
  • Woodcock, Ashley1
  • Bleecker, Eugene R2
  • Lötvall, Jan3
  • O'Byrne, Paul M4
  • Bateman, Eric D5
  • Medley, Hilary6
  • Ellsworth, Anna7
  • Jacques, Loretta6
  • Busse, William W8
  • 1 Institute of Inflammation and Repair, University of Manchester, University Hospital of South Manchester, Manchester, England. Electronic address: [email protected]
  • 2 Center for Genomics and Personalized Medicine, Wake Forest School of Medicine, Winston-Salem, NC.
  • 3 Krefting Research Centre, University of Gothenburg, Gothenburg, Sweden. , (Sweden)
  • 4 Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada. , (Canada)
  • 5 Department of Medicine, University of Cape Town, Cape Town, South Africa. , (South Africa)
  • 6 Respiratory Medicines Development Centre, GlaxoSmithKline, London, England.
  • 7 Quantitative Sciences Division, GlaxoSmithKline, Research Triangle Park, NC.
  • 8 Department of Medicine, University of Wisconsin-Madison, Madison, WI.
Type
Published Article
Journal
CHEST Journal
Publisher
Elsevier
Publication Date
October 2013
Volume
144
Issue
4
Pages
1222–1229
Identifiers
DOI: 10.1378/chest.13-0178
PMID: 23846316
Source
Medline
License
Unknown

Abstract

The efficacy of once-daily FF/VI was similar to bid FP/SAL in improving lung function in patients with persistent asthma. No safety issues were identified.

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