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Efficacy and safety of anti-D for immune thrombocytopenic purpura in children.

Authors
  • Naithani, Rahul
  • Kumar, Rajat
  • Mahapatra, M
  • Tyagi, Seema
  • Mishra, Pravas
Type
Published Article
Journal
Indian Pediatrics
Publisher
Springer-Verlag
Publication Date
Jun 01, 2010
Volume
47
Issue
6
Pages
517–519
Identifiers
PMID: 20019392
Source
Medline
License
Unknown

Abstract

This study was conducted in 20 children (16 males) (mean age 9.2 +/- 4.34y) with immune thrombocytopenic purpura (ITP) to assess the response to anti-D immunoglobulin. Six patients had newly diagnosed ITP, 6 had persistent ITP and 8 had chronic ITP. The overall response rate was 70% (14/20). The median time to response was 3 days (1-13 days). Response to anti-D was not related to age, sex, severity of bleeding, platelet counts at presentation, ABO blood group, or prior steroid or IVIG response.

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