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The Efficacy of Ketogenic Diet and Associated Hypoglycemia as an Adjuvant Therapy for High-Grade Gliomas: A Review of the Literature.

Authors
  • Varshneya, Kunal1
  • Carico, Christine1
  • Ortega, Alicia1
  • Patil, Chirag G2
  • 1 Center for Neurosurgical Outcomes Research, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center.
  • 2 Cedars-Sinai Medical Center.
Type
Published Article
Journal
Cureus
Publisher
Cureus, Inc.
Publication Date
February 2015
Volume
7
Issue
2
Identifiers
DOI: 10.7759/cureus.251
PMID: 26180675
Source
Medline
Keywords
License
Unknown

Abstract

Recent clinical findings have demonstrated that induced hypoglycemia and ketogenic diet are tolerable and can potentially be an adjuvant to standard treatments, such as surgery and chemoradiation. Other findings have advocated for KD as a malignant cell growth inhibitor, and indicate that further studies analyzing larger cohorts of GBM patients treated with a KD are needed to determine the breadth of impact a KD can have on GBM treatment.

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