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[Effects of tacrolimus vs cyclosporin-A on bone metabolism after kidney transplantation: a cross-sectional study in 28 patients].

Authors
  • Albano, Laetitia
  • Casez, Jean-Paul
  • Bekri, Soumeya
  • Gigante, Marc
  • Champenois, Isabelle
  • Cassuto-Viguier, Elisabeth
  • Jaeger, Philippe
Type
Published Article
Journal
Néphrologie & Thérapeutique
Publisher
Elsevier
Publication Date
May 01, 2005
Volume
1
Issue
2
Pages
115–120
Identifiers
PMID: 16895674
Source
Medline
License
Unknown

Abstract

BMD is not lower in FK506- than in CsA-treated patients although exposure to hyperparathyroidism was longer and estradiol levels were lower in the FK506 than in the CsA group. These data suggest that FK506 may have a favorable bone effect to compensate for these deleterious factors. This hypothesis remains to be tested in longitudinal studies.

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